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KMID : 0363220090470050570
Korean Journal of Dermatology
2009 Volume.47 No. 5 p.570 ~ p.575
Neuro-Sweet`s Syndrome with Central Nervous System Involvement
Kim Jae-Wang

Abstract
Sweet¡¯s syndrome is an acute reactive condition that is characterized by fever, neutrophilic leukocytosis, erythematous tender edematous plaques or papules, and a dense dermal infiltrate of mature neutrophils. Although the extracutaneous manifestations of Sweet¡¯s syndrome are commonly seen in the joints and eyes, the central nervous system is rarely involved. A novel concept designated "Neuro-Sweet¡¯s syndrome" has recently been proposed for those cases of Sweet¡¯s syndrome that involve the central nervous system. It is essential to evaluate the skin eruptions in patients with recurrent meningoencephalitis of an unknown origin in order to avoid unnecessary empiric therapy. Herein, we report on two men who suffered from acute recurrent meningoencephalitis and they were subsequently diagnosed as having Neuro-Sweet¡¯s syndrome.
KEYWORD
Central nervous system, Neuro-Sweet`s syndrome
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